Explained! Nobel Prize in Physiology or Medicine 2025|| How Peripheral Immune Tolerance works?

10 minute video explaining The Nobel Prize in Physiology or Medicine for 2025 that honors three researchers—Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi—for their revolutionary discoveries concerning peripheral immune tolerance. Their work revealed how the body’s powerful immune system is prevented from attacking its own tissues by identifying the specific cellular “security guards” responsible for this crucial regulation. Their insights have laid the foundation for developing new treatments for cancer and autoimmune diseases. 00:00 Introduction Nobel Prize in Physiology or Medicine for 2025 winners 00:20 Shimon Sakaguchi: The Discovery of Regulatory T Cells 00:35 How T cell works? 01:39 What is central tolerance? 02:50 Sakaguchi experiment 1 04:22 Experiment 2: The Discovery of Regulatory T Cells 05:49 Mary E. Brunkow and Fred Ramsdell: The Discovery of Foxp3 gene 07:37 Human IPEX disease and Scurvy disease 08:33 How Regulatory T Cells protect us? 09:25 Summary What is Peripheral immune tolerance? 10:09 Significance of Nobel Prize 2025 Happy Learning✌️@biologyexams4u =============================================================== We really appreciate your support 👍 Thank you so much :) ▶Enroll now. Our free certificate course on Introduction to Recombinant DNA Technology https://alison.com/course/introduction-to-recombinant-dna-technology?utm_source=alison_user&utm_medium=affiliates&utm_campaign=22177687 📙Introduction to Recombinant DNA Technology – Download free E Book