Pedigree Chart Autosomal Recessive Disorders

Characteristics of Autosomal Recessive Trait:

• Appears in both sexes with equal frequency.
• Trait tends to skip generations.
• Affected offspring are equally born to unaffected parents.
• When both parents are heterozygous, approximately 1/4 of the offspring will be affected.
• Appears more frequently among the children of consanguine marriages.

Example of Autosomal recessive Trait

Sickle cell Anemia

Albinism, Cystic fibrosis, Alkaptouria, Phenylketonuria and more

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