Ehlers Danloas syndrome is a heterogenous group of generalized tissue disorders that result from inheritable defects in the metabolism of fibrillar collagen molecules. Symptoms can include stretchy skin, loose joints and vascular problems.
Osteogenesis imperfecta, also known as brittle bone syndrome is also a heterogenous group of inherited disorders involving mutations in the collagen genes themselves that is distinguished by bone that easily bend and fracture. Retarded wound healing and a rotated and twisted spine, leading to a humped back appearance, are common features of the disease.
Scurvy (Vitamin C deficiency)
Lathyrism - sweet pea contain a chemical beta aminopropionitrate inhibit the lysyl oxidase preventing the cross linking of the tropocollagen molecules.