41. The time required to kill 90% of the microorganisms or spores in a sample under specified conditions is
A) L value
B) D value
C) K value
D) M value
42. Choose the correct statement
about T lymphocytes:
A) Both CD4
and CD8 glycoproteins are expressed on the surface of all T lymphocytes
B) T cells
displaying CD4 generally functions as TH cells, whereas those displaying CD8
generally functions as Tc cells
C) T cells
displaying CD4 generally functions as TC cells, whereas those displaying CD8
generally functions as TH cells
D) Neither
CD4 nor CD8 is expressed on T lymphocytes
43. Choose the correct statements:
1) TH cells
are class II MHC restricted and Tc cells are class I MHC restricted
2) TH cells
are class I MHC restricted and Tc cells are class II MHC restricted
3) All
nucleated cells express class II MHC molecules and expression of class I MHC
molecule is limited to antigen-presenting cells
4) All
nucleated cells express class I MHC molecules and expression of class II MHC
molecule is limited to antigen-presenting cells
A) Only 1 & 3
B) Only 2 & 3
C) Only 1 & 4
D) Only 2 & 4
44. Choose the statements which are
correct about monoclonal antibody:
1) They are
specific for a single epitope
2) Comprises
a mixture of antibodies, each specific for a particular epitope, produced from
a variety of B-cell clones
3) It is
easy to purify monoclonal antibody from polyclonal antibody preparation
4) Have
research, diagnostic and therapeutic applications
A) Only 1 & 4
B) Only 1, 2 & 4
C) Only 1 & 3
D) All are correct
45. The drug, aminopterin, in the HAT
medium blocks ------.
A) DNA repair mechanism
B) Cell-cell fusion
C) Nucleotide synthesis
D) Antibody production
46. A patient with myasthenia gravis
disease produce auto-antibodies that bind with:
A) Histone proteins
B) Acetylcholine receptor
C) TSH receptor
D) Fc region of IgG
47. The method that can be employed
effectively to analyse the diffusion rate of membrane proteins:
A) Patching and capping
B) Immuno diffusion
C) FRAP
D)
Patch-clamp
48. Individual variations in response
to a drug are responsible for the high failure rates of new drug molecules at
the clinical trial stage. What might be the reason for this individual
variation?
A)
Variations in the structure of the target molecule
B)
Differences in the way that a particular drug is adsorbed and distributed
C) Differences
in their metabolism and excretion
D) All of
the above
49. After a certain dosage level of
the drug, any further increase in the dosage of the drug, shows no additional
effect. This is known as-----.
A) Ceiling
effect
B) Null
effect
C) Threshold
effect
D) Dose
effect
50. Resistance of a population to the
infection and pathogen spread due to the immunity among the large percentage of
the population is called:
A) Passive
immunity
B) Acquired
immunity
C) Secondary
immunity
D) Herd immunity
Answers:
41. B) D value
42. B) T cells displaying CD4 generally functions as TH cells, whereas those displaying CD8 generally functions as Tc cells
43. C) Only 1 & 4
44. A) Only 1 & 4
45. C) Nucleotide synthesis
46. B) Acetylcholine receptor
47. C) FRAP
48. D) All of the above
49. A) Ceiling effect
50. D) Herd immunity
