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SET Biotechnology MCQ - PG Level Questions 41-50

41. The time required to kill 90% of the microorganisms or spores in a sample under specified conditions is

A) L value 

B) D value 

C) K value 

D) M value

SET Biotechnology MCQ - PG Level Questions

42. Choose the correct statement about T lymphocytes:

A) Both CD4 and CD8 glycoproteins are expressed on the surface of all T lymphocytes

B) T cells displaying CD4 generally functions as TH cells, whereas those displaying CD8 generally functions as Tc cells

C) T cells displaying CD4 generally functions as TC cells, whereas those displaying CD8 generally functions as TH cells

D) Neither CD4 nor CD8 is expressed on T lymphocytes

43. Choose the correct statements:

1) TH cells are class II MHC restricted and Tc cells are class I MHC restricted

2) TH cells are class I MHC restricted and Tc cells are class II MHC restricted

3) All nucleated cells express class II MHC molecules and expression of class I MHC molecule is limited to antigen-presenting cells

4) All nucleated cells express class I MHC molecules and expression of class II MHC molecule is limited to antigen-presenting cells

A) Only 1 & 3 

B) Only 2 & 3 

C) Only 1 & 4 

D) Only 2 & 4

44. Choose the statements which are correct about monoclonal antibody:

1) They are specific for a single epitope

2) Comprises a mixture of antibodies, each specific for a particular epitope, produced from a variety of B-cell clones

3) It is easy to purify monoclonal antibody from polyclonal antibody preparation

4) Have research, diagnostic and therapeutic applications

A) Only 1 & 4 

B) Only 1, 2 & 4 

C) Only 1 & 3 

D) All are correct

45. The drug, aminopterin, in the HAT medium blocks ------.

A) DNA repair mechanism 

B) Cell-cell fusion

C) Nucleotide synthesis 

D) Antibody production

46. A patient with myasthenia gravis disease produce auto-antibodies that bind with:

A) Histone proteins 

B) Acetylcholine receptor

C) TSH receptor 

D) Fc region of IgG

47. The method that can be employed effectively to analyse the diffusion rate of membrane proteins:

A) Patching and capping 

B) Immuno diffusion

C) FRAP 

D) Patch-clamp

48. Individual variations in response to a drug are responsible for the high failure rates of new drug molecules at the clinical trial stage. What might be the reason for this individual variation?

A) Variations in the structure of the target molecule

B) Differences in the way that a particular drug is adsorbed and distributed

C) Differences in their metabolism and excretion

D) All of the above

49. After a certain dosage level of the drug, any further increase in the dosage of the drug, shows no additional effect. This is known as-----.

A) Ceiling effect

B) Null effect

C) Threshold effect

D) Dose effect

50. Resistance of a population to the infection and pathogen spread due to the immunity among the large percentage of the population is called:

A) Passive immunity

B) Acquired immunity

C) Secondary immunity

 D) Herd immunity

Answers:

41. B) D value 

42. B) T cells displaying CD4 generally functions as TH cells, whereas those displaying CD8 generally functions as Tc cells

43. C) Only 1 & 4 

44. A) Only 1 & 4 

45. C) Nucleotide synthesis 

46. B) Acetylcholine receptor

47. C) FRAP 

48. D) All of the above

49. A) Ceiling effect

50.  D) Herd immunity

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