Pedigree chart Autosomal Dominant Disorders

Characteristics of Autosomal Dominant Disorders:

• Appears in both sexes with equal frequency.
• Both sexes transmit the trait to their offspring.
• Does not skip generations.
• Affected offspring must have an affected parent, unless they possess a new mutation.

• When one parent is affected (heterozygous) and the other parent is unaffected,  approximately 1/2 of the offspring will be affected.
• Unaffected parents do not transmit the trait.

Examples of Autosomal Dominant Disorders

• Examples: Huntington disease, Marfan syndrome