1. Which is the largest human cell?
1) Liver 2) Ovum 3) Spleen 4) Skin
2. Which of the following statement is incorrect regarding DNA methylation?
1) S-Adenosyl Methionine (SAM) is one of the most important methyl donors.
2) It is catalysed by enzymes
3) Occurs at CpG islands
4) Mainly G is methylated
3. Alu elements in human genome represent:
3) Nucleotide repeats
4) Transposable elements
4. Which of the following structures is known to maintain the shape of a cell?
5.The specific DNA sequences to which the transcription factors bind are referred to as
1) Replication elements
2) Blocking factors
3) Transcription factors
4) Regulatory elements
6. Which of the following is not an example of post translational modification?
1) Addition of prosthetic groups
2) Proteolytic Processing
3) mRNA splicing
4) Loss of signal sequences
7 . Calmodulin contributes to signal transduction by binding to
8. Crossing over occurs in which phase
1) Prophase I
2) Telophase I
4) Metaphase I
9. Which of the following growth media would you expect to result in synthesis of high levels of mRNA for the enzymes of the E. coli lac operon?
1) High glucose, high lactose
2) Low glucose, low lactose
3) High glucose, low lactose
4) No glucose, high lactose
10. Which of the following statement is incorrect about the genetic code is?
1) A codon is a triplet of nucleotides that codes for a specific amino acid
2) A specific first codon in the sequence establishes the reading frame
3) A codon specifies more than one amino acid
4) Nucleotide triplets are read in a successive, non-overlapping fashion
11. The original codon changes to stop codon in which type of mutation
1) Sense mutation
2) Mis-sense mutation
3) Non-sense mutation
4) Reverse mutation
12. What is the mode of action of exonuclease III?
1) Exonuclease III acts on single stranded DNA in 3'-5'direction
2) Exonuclease III acts on double stranded DNA in 5'-3'direction
3) Exonuclease III acts on single stranded DNA in 5'-3'direction
4) Exonuclease III
acts on double stranded DNA in 3'-5'direction
13. Human telomeres consist of Tandem repeats of sequence
2) (TTAAGGG) n
3) (MAAGG) n
1. 2) Ovum
2. 4) Mainly G is methylated
3. 4) Transposable elements
4. 2) Microtubules
5. 4) Regulatory elements
6. 3) mRNA splicing
7. 2) Calcium
8. 1) Prophase I
9. 4) No glucose, high lactose
10. 3) A codon specifies more than one amino acid
11. 3) Non-sense mutation
12. 4) Exonuclease III acts on double stranded DNA in 3'-5'direction
13. 1) (TTAGGG)n