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CSIR-UGC-NET-JRF-Life Sciences –Genetics Previous Questions

csir previous questions
(UNIT: 8 Inheritance Biology )

1. Type of genotype in individual having blood group B will be (June 2006)
a) IA Io
b) IAIB
c) Io Io
d) IB Io

2. Which is observed after crossing over between chromosomes having pericentric inversion and normal (June 2006)
a) Segmental Deletion and duplication
b) Bridge formation
c) Ring formation
d) Acentric and dicentric chromosomes

3. If a gene product in Species A is 90% similar to gene product in Species B. Such genes are termed as(June 2006)
a) Orthrologous
b) Paralogous
c) Allologous
d) Perilogous
4. Interspecific hybrids have proved very useful for (June 2006)
a) Gene mapping
b) Genetic manipulation
c) Gene structure
d) Gene function
5. Albinos have visual problem in bright light because they lacks (June 2006)
a) Melanin
b) Rods
c) Cones
d) Creatin
6. The F+ segment of bacteria may be transferred to F- bacteria by the process of (June 2006)
a) Conjugation
b) Transduction
c) Transformation
d) Fragmentaion
7. In a genetic test 9:7 ratio in F2 generation represents (June 2006)
a) Epistasis
b) Co-dominance
c) Incomplete dominanace
d) Complete dominance
8. If inheritance of disease to next generation is only possible through females. The probable inheritance is (Dec2006)
a) Sex-linked
b) Mendelian
c) Organellar
d) Autosomal
9.  Among the following Mendelian  inheritance is obeyed by (Dec2006)
a) Quantitative traits
b) Transposons
c) organelles
d) gene for vertical transfer of disease
10. If mutation changes codon in such a way that there is no effect on functioning and overall structure of protein. This type of mutation is termed as (June 2007)
a) Silent
b) Mis sense
c) Transition
d) Frame shift
11. Considering the following pedigree chart (June 2008)
pedigree
a) X linked dominant
b) Autosomal dominant
c) X linked recessive
d) Autosomal recessive


12.  Genetic disorder Xeroderma pigmentosum is due to error in (Dec 2008)
a) base  excision  repair mechanism
b)  direct repair mechanism
c) nucleotide excision repair mechanism
d) DNA replication mechanism
recessive trait-pedigree
13. The following pedigree represents the inheritance of a rare disorder. Based on the above pedigree, what is the most likely mode of inheritance? (Dec 2008)
a) X linked dominant
b) Autosomal dominant
c) X linked recessive
d) Autosomal recessive
14. Quantitative inheritance defines (Dec 2008)
a) variation in phenotype
b) variation in genotypes
c) variation in genes
d) variation in environment
15. A mother of blood group O has a group O child, the father could be of blood type
a) A or B
b) AB only
c) O only
d) A or B or O
Answers
1. IB Io

2.a) Segmental Deletion and duplication
Related key points:
  • crossing over between chromosome having pericentric inversion and normal=segmental deletion and duplication
  • crossing over between chromosome having paracentric inversion and normal=acentric and dicentric chromosomes

3. a) Orthrologous
  • Orthologs are genes that are related by vertical descent from a common ancestor and encode proteins with the same function in different species.
  • Paralogs are homologous genes that have evolved by duplication and code for protein with similar, but not identical functions.
4. a)Gene mapping

5.a) Melanin

6.a) conjugation

7.a) epistasis

8.c) Organellar

9. d) gene for vertical transfer of disease
  • vertical gene transfer: transfer of DNA from parent to offspring during normal cell division
  • horizontal gene transfer is transfer of DNA between genomes; very common in bacteria.
10.a) Silent

11. b) Autosomal dominant

12.c) nucleotide excision repair mechanism

13.d) Autosomal recessive

14.b) variation in genotypes
Quantitative inheritance / Multiple factor / Polygenic inheritance / Multiple factor / Cumulative inheritance

15. d)  A or B or O
mother: O blood group= Io Io
Child  : O blood group= Io Io
Blood group of father?
Here one allele Io comes from mother and the other from the father, ie. father can be IA Io, IB Io, Io Io
Ans: A or B or O
More about: ABO Blood group

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