JNU M Sc Biotechnology Combined Entrance Questions

1. Which of the following antibiotics acts by inhibiting bacterial cell wall synthesis?
a) Penicillin
b) Amphotericin
c) Puromycin
d) Erthryromycin
2. End labelling of DNA fragment is a prerequisite for Maxam Gilbert method of DNA sequencing. Which of the following enzymes is used in accomplishing this?
a)  Ligase
b) Taq polymerase
c) Restriction enzyme
d) Polynucleotide kinase 
3. Which  of the following states of chromatin is normally associated with active genes?
a) Euchromatin
b) Facultative heterochromatin
c) Constitutive heterochromatin
d) Centromeric heterochromatin
4. Which of the following sequence correctly describes the cell cycle? 
a) G 1 phase: G 2 phase : Mitosis: Cytokinesis
b) Mitosis: G 1 phase: G 2 phase :  Cytokinesis
c) : Cytokinesis: Mitosis: G 1 phase: G 2 phase :
d) S phase: G 2phase:  Mitosis: Cytokinesis :G 1 phase
5. The peptide hormone involved in controlling blood pressure is
a) Testosterone
b) Oxytocin
c) Vassopressin
d) Interferon B
6. Microtubules are made up of one of the following proteins
a) Albumin
b) Globulin
c) Gelsolin
d) Tubulin
7. Structure of which of the following antibiotics is similar to aminoacyl t RNA?
a) Puromycin
b) Streptomycin
c) Chloramphenicol
d) Cycloheximide

8. Which one of the following does not inhibit protein synthesis 
a) Puromycin
b) Oligomycin
c) Cycloheximide
d) Chloromphenicol
9. The Ames test is used to determine if a chemical
a)  increases the rate at which a bacterial cell divides
b) Decreases the number of cells in a culture
c) Is a potential mutagen
d) decreases the ability of a cell to photosynthesize
10.  The type of silencing involved in miRNA is
a) Replicational
b) Transcriptional
c) Post Transcriptional
d) Post Translational
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Answers
1.  a) Penicillin
2. d) Polynucleotide kinase
3. a) Euchromatin
4.  d) S phase: G 2phase: Mitosis: Cytokinesis :G 1 phase
5. c) Vassopressin
6. d) Tubulin
7. a) Puromycin
8. b) Oligomycin
9. c) Is a potential mutagen
10. c) Post Transcriptional
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